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Are you aware of a relationship between testosterone and spinal injuries?

Directed to MedFit.
People have theories that anabolic steroids might have a place in the management of spinal cord injuries, what are your thoughts.

I was shocked to read about creatine banned in France. We are seeing creatine used much more in healthcare including many muscular pathologies. I look forward to your response.
By Mike Wallace – almost 2 years ago

Replies

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Hello Mike,

Well first of all I knew nothing of what you are alluding to in your question, so I have had to do some research, and low and behold, I found this article:

Effects of co-administration of clenbuterol and testosterone propionate on skeletal muscle in paraplegic mice. (http://tiny.cc/2bkzr)

Spinal cord injuries are often related to paid and significant changes in skeletal muscle mass and properties. In the above study, they looked at the effects of clenbuterol (β2 agonist with some structural and pharmacological similarities to epinephrine and salbutamol, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug) and testosterone propionate on skeletal muscle and adipose tissue in adult, spinal cord transected mice.

The trial looked at clen alone, test alone, and then together immediately post transection. The substances were found to differentially reduce loss in body weight, muscle mass, and muscle fiber cross-sectional area (CSA) values. Although all three treatments induced significant effects, testosterone-treated animals were generally less protected against transection related changes.

None of the treatments prevented fat tissue loss or muscle fiber type conversion and functional loss generally found in transected animals. These results provide evidence suggesting that clenbuterol alone or combined with testosterone may constitute better clinically-relevant treatments than testosterone alone to decrease muscle atrophy (mass and fiber CSA) in spinal cord inured subjects.

This has not been trialed on humans, and my gut feeling is that it won't be. There are so many potential side effects to consider, all of the risks associated with anabolic steroid use and clenbuterol use. I like the thinking of the researchers, and they might be onto something, but not this drug combination in my humble opinion.
Dan Reardon
Health and Fitness Doctor
almost 2 years ago
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I don't mean to sound dismissive, as steroids have the potential for life-threatening side effects but steroid-using athletes would be more susceptible to back and other injuries due to the way they train and some studies have refuted the increased incidence of various training-related injuries related to steroid use.

I'm not in any way condoning the use of "gear" because most people in the bodybuilding industry probably under-estimate the potential side effects of these drugs but Fitness Inventor is dedicated to delivering balanced, factual information.
Mark Gilbert
Nutritionist and Supplement Specialist
almost 2 years ago

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